Sometimes a 1 has no neighboring 1 at all. Check every cell next to it, including across the wrap, and if none holds a 1 or an X, the cell is isolated.
An isolated 1 still has to be covered, so it becomes a group of one cell. A group of 2⁰ = 1 cell removes no variables, so its term is the complete minterm, with every variable present.
That's legal, and you must not skip it. A single-cell group is also automatically an essential prime implicant: it can't grow, and nothing else covers that 1.
An isolated 1 is the most expensive kind of term, so it's worth checking carefully before you accept one. Look again at:
- the cell at the other end of its row and of its column
- any don't-cares next to it, which could be used to pair it up
Functions like the odd function have every 1 isolated: their 1s form a checkerboard, and the minimal SOP is just the list of minterms.
| AB\CD | 00 | 01 | 11 | 10 |
|---|---|---|---|---|
| 00 | 1m0 | 1m1 | 0m3 | 0m2 |
| 01 | 0m4 | 0m5 | 0m7 | 0m6 |
| 11 | 0m12 | 0m13 | 0m15 | 0m14 |
| 10 | 0m8 | 0m9 | 0m11 | 1m10 |